Built by researchers, for researchers
PIXUL started with a real problem in a real lab, and became the only instrument that truly processes 96 samples in parallel.
The Origin Story
PIXUL was not designed by hardware manufacturers looking for a market. It came from practicing researchers who were frustrated by existing limitations. Dr. Karol Bomsztyk needed high-throughput sonication for Matrix-ChIP and identified the shearing step as the bottleneck preventing experiments from scaling beyond a handful of samples.
Dr. Tom Matula at the University of Washington Center for Industrial and Medical Ultrasound engineered the solution: an array of paired acoustic transducers, each dedicated to a column of a standard 96-well plate, operating at 2 MHz megasonication frequency. The result was Matchstick Technologies, which developed the PIXUL Multi-Sample Sonicator.
Active Motif, a company with 25+ years of experience developing tools for epigenetics, gene regulation, and genomics research, licensed the technology and brought PIXUL to market. Today, approximately 95 instruments are installed in labs across the Americas, Europe, and Asia-Pacific.
About Active Motif
Active Motif develops tools and services for epigenetics, gene regulation, and genomics research. Based in Carlsbad, California, with operations in Europe and Asia, Active Motif serves researchers worldwide with antibodies, assay kits, recombinant proteins, and instrumentation, including the PIXUL Multi-Sample Sonicator and downstream kits for ChIP-seq, CUT&Tag, ATAC-seq, and more.
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